eLife1d
HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity
Abstract Research of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia (FM), two acquired chronic illnesses affecting mainly females, has failed to ascertain their frequent ...
Too Old to Operate3d
Nuclear ANLN regulates transcription initiation related Pol II clustering and target gene expression.
Anillin (ANLN), a mitotic protein that regulates contractile ring assembly, has been reported as an oncoprotein. However, the function of ANLN in cancer cells, especially in the nucleus, has not been ...
Nature3d
Breaking the chains: structure and function of the deubiquitinases
Ubiquitylation is a reversible post-translational modification involved in a myriad of cellular functions. A superfamily of approximately 100 ubiquitin-specific proteases, called deubiquitylating ...
Nature6d
RNA splicing articles from across Nature Portfolio
RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns, splicing ...
Frontiers3d
New Era of Studying RNA Secondary Structure and Its Influence on Gene Regulation in Plants
The dynamic structure of RNA plays a central role in post-transcriptional regulation of gene expression such as RNA maturation, degradation, and translation. With the rise of next-generation ...
Frontiers3d
Detection and Functional Verification of Noncanonical Splice Site Mutations in Hereditary Deafness
991-15_991-13del in DFNA5, c.6087-3T > G in PTPRQ and c.164+5G > A in USH1G. All six variants were predicted to affect the RNA splicing by at least one of the computational tools Human Splicing Finder ...