Since the nineteenth-century drawings of neurons by the neuroscientist Santiago Ramón y Cajal, the brain has been ... The rise of single-cell RNA sequencing (scRNA-seq) over the past decade ...

There was a very intimate connection." To better characterize the cellular components of brain cancer, investigators performed single-cell RNA sequencing on tissue samples from 33 types of brain ...

This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...

Immune therapy has transformed how cancer is treated, but many tumors continue to evade these treatments, thanks to their resemblance to healthy tissue.

"We used several advanced research methods, such as single-cell RNA sequencing and spatial transcriptomics ... While there are still a few questions remaining regarding these cells, that we ...

"We used several advanced research methods, such as single-cell RNA sequencing and spatial transcriptomics ... While there are still a few questions remaining regarding these cells that we ...

Data normalization is vital to single ... in RNA-Seq or other sequencing-based comparative genomic experiments. SAMstrt is developed on this method and alters the sequencing depth estimation by ...

This parent-child relationship helps regulate brain regeneration and repair. The study also reveals that calcium signaling plays a key role in how NSCs decode multiple signals from their environment.

Many studies have used single-cell RNA sequencing (scRNA-seq) to infer gene regulatory networks (GRNs), which are crucial for ...

In recent years, scientific advancements have transformed our understanding of diseases, particularly at the cellular level.

This study is the first to demonstrate that certain tRNA introns influence gene expression. Scientists have discovered that ...