Small molecule targeted ... A bispecific antibody (GPC3-S-Fabs) was reported to recruit NK cells to target GPC3 positive cancer cells. Besides, bispecific T-cell Engagers (BiTE), including GPC3/CD3, ...

Once a peptide has been identified that binds with high affinity and specificity to an antibody antigen binding fragment (Fab), crystal structures ... the candidate linear epitope which represents a ...

The antibody molecule in particular ... using only CDR-encoding gene fragments originating from sequences formed and “proofread” in vivo. Such proofread peptide sequences that have evolved ...

In this roundtable discussion, an expert panel will discuss how the latest applications of aptamer technology are enabling innovation across the life sciences by replacing antibodies. In this webinar, ...

The company develops fully human albumin binding technology, which utilizes human single chain antibodies fragment that binds to and hitch-hikes on human serum albumin for transport to target tissues.

Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, ...

The Geminid meteor shower peaks overnight on Dec. 13 and Dec. 14. The Geminids are active between Nov. 19 to Dec. 24 each year. This year, the moon will not interfere too much with Geminid meteor ...

is an enhanced sampling molecular dynamics technique that has been previously effectively applied to refine protein or RNA-small-molecule docking poses. This study presents the first application of ...

Aim: Antibody fragments, appropriately formulated, can penetrate through the ocular surface and thus have potential as therapeutic agents. The aim was to investigate the influence of protein fragment ...