Figure 1. During sepsis, liver macrophages (Kupffer cells) in hepatic sinusoids synthesize large amounts of inflammatory cytokines (TNF-α, IL-6, IL-1β) through the TLR4-MyD88/NF-κB pathway. Moreover, ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

Hepatocellular carcinoma (HCC) mostly occurs in the background of liver fibrosis, and activated hepatic stellate cells (HSCs) exist in HCC tissues and adjacent tissues. HSC activation is involved ...

Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to ...

Listen to more stories on the Noa app. The human cell is a miserable thing to study. Tens of trillions of them exist in the body, forming an enormous and intricate network that governs every ...

Jan. 30, 2025 — A new study has highlighted the potential of resveratrol, a natural compound found in grapes, blueberries, and raspberries, to enhance female fertility. The systematic review ...

Cell C has disclosed that it was the victim of a cyberattack that exposed the data of a limited number of people. The mobile network operator did not reveal further details about the breach.

According to precedent and due to his status, Yoon will probably be assigned a solitary cell, likely bigger and better appointed than the standard 6.56 square metre (71 square feet) single cells.

It feels like the Splinter Cell remake has been on its way for a while now, which isn't helped by the fact it's been over three years since we heard anything official about the game. From what we ...