Fibrosis was measured in this study both subjectively, in a manner congruent with other population-based,9 ARDS,7 SARS-CoV-14 and COVID-191 2 6 10 studies, as well as objectively using texture ...

TGF-β1 is a strong pro-collagenogenic factor and contributes to the development of hepatic fibrosis 17, 18. Moreover, the expression of TGF-β1 in liver tissues correlates with the pathological degree ...

Objective Extracellular matrix protein 1 (ECM1) serves as a gatekeeper of hepatic fibrosis by maintaining transforming growth factor-β1 (TGF-β1) in its latent form. ECM1 knockout (KO) causes latent (L ...

RALEIGH, N.C. — When he was about 14, Pete Proimos learned a soul-crushing statistic about the cystic fibrosis he’d endured since birth: Patients back then didn’t live much past high ...

A SPANISH research team has developed a non-invasive, urine-based biomarker model that accurately predicts the degree of tubulointerstitial fibrosis in patients with primary IgA nephropathy (IgAN), ...

CAMBRIDGE, Mass., June 3, 2025 /PRNewswire/ -- Artificial intelligence (AI) is rapidly transforming the pharmaceutical industry, reshaping the landscape from target identification to personalized ...

On June 3, 2025, the industry's first proof-of-concept clinical validation of AI-driven drug discovery was published in Nature Medicine.Insilico Medicine and collaborators reported promising safety ...

“Cystic Fibrosis involving your pancreas and what that happens is then you don’t produce enough enzymes and you don’t absorb fat, vitamins and other nutrients that is necessary for you to grow,” says ...