Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A ...

A breakthrough assay is advancing how researchers observe gene expression in real time. Named QRIVTA (quantitative real-time ...

Maintaining high transcriptional fidelity is essential to life. For all eukaryotic organisms, RNA polymerase II (Pol II) is responsible for messenger RNA synthesis from the DNA template. Three key ...

In this study, a whole-course nucleic-acid-constructed biosensor that combines the all-in-one concepts of the universal blocking linker recombinase polymerase amplification (UBLRPA) and a peptide ...

These include the promoter, plus response elements, activator and enhancer sequences for binding of transcription factors to aid RNA polymerase binding and promote expression, and operator or ...

A new study reveals that blocking ribosomal RNA production rewires cancer cell behavior and could help treat genetically ...

New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.

A new tool called PHOTON, developed by scientists at UT Southwestern Medical Center, can identify RNA molecules at their native locations within cells—providing valuable clues to where different ...

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Abstract The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key ...

Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...