Villin-type headpiece domains are ∼70 residue motifs that reside at the C-terminus of a variety of actin-associated proteins. Villin headpiece (HP67) is a commonly used model system for both ...

Abstract The villin headpiece subdomain (HP36) is the smallest naturally occurring protein that folds cooperatively. The protein folds on a microsecond time scale. Its small size and very rapid ...

They also found that after the extra chromosome was removed, genes tied to nervous system development were more active and those related to metabolism were less active. This backs up previous ...

We used the Cre- loxP chromosome engineering strategy 15 to generate the inversion in mouse embryonic stem (ES) cells by successive gene targeting of a loxP site to the two endpoints, followed by ...

Summary: Authors in this study previously reported that BYL719, an inhibitor of PI3Kα, suppressed heterotopic ossification in mice model of a human genetic disease, fibrodysplasia ossificans ...

Cryo-electron microscopy (EM), proximity ligation assay (PLA), and site-directed mutagenesis were used to explore the mechanism of RhoA activity regulation. VSMC, hypertensive animal models, Trpv4-/- ...

Golub & Co.'s McKenzie Parker, Neoscape's Jason Thompson, Taylor Johnson Public Relations' Emily Johnson, R2 Cos.' Matt Pistorio, 1905 New Media's Ginna Ryan and SVN Chicago's Elana Napp.