used micro-imaging techniques – including X-ray crystallography and cryo-electron microscopy – to determine the structure of the DNA packaging motor in a virus called Bacteriophage phi29.
Research interests: assembly and structure determination of viruses, virus-receptor interaction, antivirals, neutralizing antibodies, electron cryo-microscopy, image processing, crystallography. Sarah ...
Viruses, like those that cause COVID-19 or HIV, are formidable opponents once they invade our bodies. Antiviral treatments ...
It’s the same when doctors, researchers and epidemiologists fight any virus: The physical structure of its molecules ... are able to physically look at viruses using massive cryo-electron microscopes.
Using cryo-electron microscopy, the researchers mapped how the Sudan virus interacts with the human NPC1 receptor ... More information: Fan Bu et al, Cryo-EM structure of Sudan ebolavirus glycoprotein ...
University of Manchester scientists have produced the world’s most powerful optical microscope, which could help understand the causes of many viruses and diseases. Writing in the journal Nature ...
The imaging revealed both the hollow structure of T4's capsid and tail - details previously visible only with electron ... virus that evolved to infect bacteria turns out to possess exactly the ...
‘Filming’ viruses at atomic resolution Filoviruses, such as the Ebola virus and Marburg virus ... A combination of cryo-electron microscopy and high-speed atomic force microscopy allows ...
Transmission electron microscopy generates an image of the internal structure of a thin sample. Scanning electron microscopy generates a topological image of a sample. PRC2-dependent H3K27 ...
The varying degrees of electron ... crystal structure, and defects of materials. It is highly valued for its ability to provide detailed images of the internal structure of samples. Both STEM and TEM ...