The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

From being a promising yet underexplored approach in the 1990s, mRNA therapeutics have evolved dramatically. The discovery of ...

2.6 Expression level of mRNA by RT−qPCR mRNA was isolated from 6-well plate cells with 90~100% confluency. cDNA was reversely transcribed by RT SuperMix kit (Vazyme, Nanjing, China). RT−qPCR was ...

Cells from different donors (n = 4) were stimulated with mechanical strain (15% elongation, 1 Hz) and lncRNA qPCR Array (ArrayStar) was performed. The amount of lncRNA HOTAIR and SIRT1 mRNA was ...

The expression of LRRC8 family members (A to E) was measured by reverse transcription (RT) qPCR. mRNA specimens were isolated from the cells grown on collagen-gel in 24-well dishes using a NucleoSpin ...

In this study we investigated endoscopic mucosal biopsy derived mRNA expression to identify a “gene expression ... each of the top five probes derived from the combined analysis by qPCR. TNFRSF11B is ...

There have been 67 confirmed human bird flu cases in the U.S. since April 2024. Moderna has been awarded approximately $590 million from the federal government to help speed up the development of ...

Moderna (NASDAQ:MRNA) was among the notable gainers on Wednesday after Oracle (NYSE:ORCL) Chairman Larry Ellison highlighted the AI's potential in the development of messenger RNA-based cancer ...

Oracle Chairman Larry Ellison highlighted the potential medical benefits of the investment, stating that AI could be used to detect cancers and customize mRNA vaccines to treat them within 48 hours.

Occasionally, these molecular decoders pause on the mRNA, either because they are instructed to do so or they have difficulty traversing the sequence. Previous studies that investigated these events ...