Nanoparticles (NPs) are materials whose dimensions range from 1 to 1,000 nanometers (nm). Due to their nano-scale dimensions and tunable material properties, NPs have gained interest in the global ...

FcRn protects IgG and albumin from catabolism, transports IgG across the placenta, and regulates IgG function. Blocking or augmenting FcRn can decrease autoimmune antibodies and enhance drug delivery.

Using native human IL-18 binding protein may reduce immunogenic potential compared to traditional monoclonal antibodies, and this serum albumin-binding fusion protein may allow for more effective ...

Albumin-based biofunctionalized biosensors have the potential to be utilized for the detection of physiological ligands (e.g., heme) and pathogenic proteins. In human cells, heme is always bound to ...

EPO grants Sonnet EU Patent No. EP3583125 B1 for Fully Human Albumin Binding (FHAB®) domain fusion proteins, expanding global IP protection.

Interestingly, albumin extensively modified by advanced glycation end products (AGE-albumin), which is an established SR-BI ligand known to accumulate in renal disease, only weakly interfered with HDL ...

While traditionally used as a marker for nutritional status, albumin is a protein that is mostly responsible for oncotic pressure regulation and ligand binding and transport. 1 Low serum albumin ...

Some albumin-binding groups, such as Evans Blue, have been employed to extend aptamers' circulation for cancer diagnosis. But the difficulty of chemical modification and the uncertain biotoxicity of ...

Human serum albumin (HSA) is the main zinc (II) carrier in blood plasma. The HSA site with the strongest affinity for zinc (II), multi-metal binding site A, is disrupted by the presence of fatty acids ...

Albumin domain mutants with enhanced A β binding capacity identified by phage display analysis for application in various peripheral A β elimination approaches of alzheimer’s disease treatment.

Quantitative measurements of biomolecule associations are central to biological understanding and are needed to build and test predictive and mechanistic models. Given the advances in high-throughput ...