1Cellular Degradation Biology Center, College of Medicine, Seoul National University, Seoul, Republic of Korea. 2Department of Biomedical Sciences, College of Medicine, Seoul National University, ...

Background: The Beclin-1/Bcl-2 complex plays a pivotal role in regulating both autophagy and apoptosis in osteoblasts affected by osteoporosis. This study first investigates whether the Bushen Jianpi ...

Additionally, significant alterations in mitochondrial morphology were observed, which may indicate dysfunction and sarcopenia. Scientists have identified that the decrease of certain ...

Transient Ca 2+ fluctuations on the surface of the endoplasmic reticulum (ER) can induce liquid-liquid phase separation (LLPS) of the autophagy initiation complex FIP200, forming FIP200 puncta and ...

Besides the autoregulatory process, other processes contribute to keep steady-state levels; nucleocytoplasmic transport, LLPS, mitochondrial function, autophagy and RNA binding all have been shown to ...