which are linked to imbalances in lipid and protein production and degradation. Furthermore, improving autophagy function has the potential to slow cellular ageing by preserving organelle quality ...

which are linked to imbalances in lipid and protein production and degradation. Furthermore, improving autophagy function has the potential to slow cellular aging by preserving organelle quality ...

Full Meeting Abstract: This keystone symposium will focus on advances in the rapidly evolving fields of targeted protein degradation and chemically ... that hijack other cellular processes, including ...

TFE3 overexpression attenuates α-Syn toxicity in a mouse model of Parkinson's disease. TFE3 overexpression rescues autophagy defects of dop ...

Longevity research has propelled the scientific community to concentrate on interventions that do more than simply add years ...

Key Laboratory of Functional Polymer Materials of Ministry of Education, State Key Laboratory of Medicinal Chemical Biology, Institute of Polymer Chemistry and College of Chemistry, Nankai University, ...

Autophagy can lead to disease progression in advanced ... PROTAC targeting the estrogen receptor alpha (ERα), which was shown to induce degradation of the ERα protein in MCF-7 breast cancer cells.