June 20, 2025) - Thiogenesis Therapeutics, Corp. (TSXV: TTI) (OTCQX: TTIPF) ("Thiogenesis" or the "Company"), a clinical-stage biopharmaceutical company developing sulfur-based therapeutics for rare ...

Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes ("MELAS") is an inherited mitochondrial disorder, most often caused by a mutation of m.3243A>G in the MT-TL1 gene in ...

Case Records of the Massachusetts General Hospital from The New England Journal of Medicine — A 72-Year-Old Woman with Altered Mental Status and Acidemia ...

The presence of acidosis may have adverse effects on the cardiovascular system because acidosis decreases myocardial contractility, 7 decreases the responsiveness of the myocardium and peripheral ...

Background: Predicting at birth which infants with perinatal hypoxic–ischaemic injury will progress to significant encephalopathy remains a challenge. Objective: To determine whether lactic acidosis ...

Type B lactic acidosis is a rare and often fatal complication seen in patients receiving the nucleotide analogues zidovudine, stavudine, didanosine, and lamivudine.

Type A lactic acidosis is characterized by overproduction of lactic acid due to a significant lack of oxygen reaching vital organs—what's known as systemic or widespread hypoperfusion. Type B lactic ...

Keywords: lactate, acidosis, focal slowing, electroencephalogram, structural lesions, epilepsy Citation: Chegodaev DA and Pavlova PA (2024) High lactic acid levels in the brain contribute to the ...

ABSTRACT: Cyanide poisoning is one of the most dangerous poisonings, and it can be absorbed into the body through the mouth, inhalation and through the skin. A 32-year-old female patient was admitted ...

Type B lactic acidosis is not associated with a lack of oxygen and is subdivided into three categories. B1 is associated with systemic diseases such as diabetes or renal failure. B2 is related to drug ...