Every second, an adult generates around five million new blood cells to replace aging or dying ones, ... Continuous map of early hematopoietic stem cell differentiation across human lifetime.

In blood stem cell differentiation, single-cell transcriptomics and imaging-based studies have demonstrated that key TFs are expressed in smooth, ...

More specifically, they captured “hundreds of clonal differentiation trajectories across tens of individuals and 230,358 single cells.” In young blood, thousands of different stem cells ...

Discovery of CXCL12’s role in red blood cell development could revolutionize artificial blood production and help address ...

A breakthrough in the understanding of how mammals create red blood cells could lead to opportunities for artificial blood to ...

Unexpected mutations in blood stem cells may help protect against Alzheimer’s disease. A new study published in the journal ...

This process, called differentiation, takes about two weeks and makes millions of blood cells, he says. These cells were then infused into mice that lacked an immune system and became functional ...

Researchers from the Stem Cells and Cancer team at the Josep Carreras Leukaemia Research Institute and the Hospital del Mar Research Institute have developed a method to confidently produce blood ...