Scientists have created the most detailed 3D map of a mouse brain ever produced, a milestone that could revolutionize ...

In non-human primate (NHP) studies to date, a single IV infusion of CAP-003 resulted in dose-dependent increases in GCase activity in critical brain regions including the substantia nigra, frontal ...

In a nutshell Both too little and too much exercise can accelerate brain aging. The study found a U-shaped relationship where people who were sedentary and those who exercised excessively both showed ...

Comparative analysis of brain connectivity in autism and ADHD. Credit: Nature Mental Health (2025). DOI: 10.1038/s44220-025-00431-5 ...

However, not all connectivity differences were specific to generalized anxiety disorder. In some cases, the same connectivity patterns were seen in youth with other conditions, such as depression or ...

Structural MRI scans assessed the volume of several brain regions of the brain’s subcortex, including the amygdala, hippocampus, caudate, accumbens, pallidum, putamen and thalamus.

There were about 50% fewer interneurons (specialized brain cells that help regulate the pace of brain electrical activity) in the caudate-putamen region within the basal ganglia, which is crucial ...

This is the first time that brain tissue has been cryogenically frozen and revived without damage. In a process called vitrification, researchers treated slices of mouse brains with ...

Slices of mouse brain that were kept at -150°C for up to a week have shown near-normal electrical activity after being warmed up. The results could take us a step closer towards cooling and ...

High signal in caudate/putamen on magnetic resonance imaging (MRI) brain scan and/or at least two cortical regions (temporal, parietal, occipital) either on diffusion-weighted imaging (DWI) or ...

Coronal brain slice showing projections from different visual areas in the cerebral cortex to the ventrolateral geniculate nucleus (vLGN). These pathways are part of the circuit identified as ...

Brain imaging showed atrophy in the caudate and putamen at this time point. A longitudinal increase in the somatic cytosine-adenine-guanine repeat expansion ratio in blood predicted brain atrophy.