Adding bile acids as farnesoid X receptor agonists to the culture medium supported the growth and development of unique stem ...

A breakthrough in the understanding of how mammals create red blood cells could lead to opportunities for artificial blood to ...

Study identifies proximity-based mechanism behind LAG-3 inhibition and introduces novel bispecific antibody for autoimmune ...

Four days ahead of its July 7 PDUFA date, the U.S. FDA granted accelerated approval to Dizal (Jiangsu) Pharmaceutical Co. Ltd.’s sunvozertinib (DZD-9008), branded as Zegfrovy, for treating adults with ...

Drug discovery can be a long and complex process. Medicines for neurodegenerative diseases like Alzheimer's disease are among ...

This valuable manuscript investigates the localisation of nutrient receptors in bloodstream stage trypanosomes, with implications for both nutrient uptake and immune evasion. Results after direct ...

Kennedy researchers have uncovered key design parameters for bispecific T-cell engagers (TcEs)—a class of cancer immunotherapy drugs. The findings may help unlock the full potential of TcEs and ...

Membrane receptors, particularly G protein-coupled receptors (GPCRs), are integral to numerous physiological processes. Precise control of the receptor endocytosis is essential for understanding ...

Receptor–ligand interactions on cell membrane play key roles in many physiological and pathological processes, especially in the nanodrug targeted delivery system. Hyaluronic acid (HA) is the main ...