The discovery that RIPK1 deficiency sensitizes the liver to acute injury and hepatocyte apoptosis is based on convincing evidence, highlighting the importance of RIPK1 in maintaining liver homeostasis ...

Data Synthesis: Autoimmune hepatitis can present acutely and have histologic features of centrilobular zone 3 inflammation. Many patients may be asymptomatic, but they frequently have severe or ...

Liver biopsy showed severe iron deposited predominantly in hepatocytes with a decreasing gradient from periportal zone 1 to centrilobular zone 3, and iron deposits in few Kupffer cells (Figures 1A, B) ...