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The Sistine Chapel is ready to host the cardinals who will gather on Wednesday for the conclave to elect the next pope after the death of Pope Francis on April 21 at the age of 88. (Video courtesy ...

NPR's Scott Detrow speaks with art historian Kim Butler about the artwork that adorns the walls of the Sistine Chapel and its significance ahead of the conclave to elect the next pope.

The most famous scene in the Sistine Chapel is The Creation of Adam. Part of Michelangelo's ceiling paintings, the fresco depicts God giving life to Adam.

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The Creation of Adam is traditionally thought of as illustrating the Biblical creation narrative from the Book of Genesis in which God breathes life into Adam, the first man.