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Cystic fibrosis is caused by hereditary genetic mutations that impair or ... This could explain why defective immune reactions cannot be treated well with novel CFTR modulator therapies.

Despite new medication, cystic fibrosis often leads to permanent lung damage. Working with an international team, researchers ...

Sionna Therapeutics has closed its initial public offering, raising $191 million for its pipeline of therapies for cystic ...

Viral and nonviral clinical trials have established proof-of-principle for gene transfer into the cystic fibrosis (CF) lung. It is currently unknown whether gene transfer efficiency is sufficient ...

We applied a strategy of serial screening steps to 45 patients with congenital absence of the vas deferens and characterized cystic fibrosis transmembrane conductance regulator gene mutations in ...

and we hope future research could lead to the development of genetic therapy treatments for those with rarer CF mutations too,” said Lucy Allen, a lung biologist and research director at Cystic ...

Days before three scientists at Boston-based Vertex Pharmaceuticals will share a $3 million prize for revolutionizing the treatment of cystic fibrosis, the award — sometimes called the Oscars of ...

Both tests were positive. Cystic fibrosis is a genetic disorder caused by a defective protein, CFTR, that makes mucus overly ...

Sionna is working on a medicines it claims can challenge Vertex Pharmaceuticals’ dominant cystic fibrosis business. The company designed its therapies to stabilize a tough-to-drug region of the CFTR ...

Despite new medication, cystic fibrosis often leads to permanent lung damage. Working with an international team, researchers from the Technical University of Munich (TUM) have discovered that the ...