Overall, our results point to a complex interplay among nuclear receptor ligands, cytosine methylation, and the metabolome in both the induction and mitigation of epiboly defects induced by TDCIPP.

The addition of a single methyl group to adenine or cytosine bases in DNA can have profound biological consequences in organisms ranging from microbes to man. For example, alteration in gene ...

Long-term, persistent weekly or more frequent cannabis smoking leaves a distinct and partially reversible epigenetic ...

The i -motif structure consists of four cytosine-rich DNA strands, bound in antiparallel orientation by cytosine-cytosine + base pairs. (26) Consequently, formation of i -motifs is often observed at ...

Analysis of human centromeric alpha-satellite DNA showed a variable cytosine methylation profile suggestive of a distinct domain organization 10.