DNA methylation: ox-LDL promotes DNA methylation at the eNOS promoter ... genes; ORL1, opioid receptor like-1; LOX-1, lipoprotein receptor-1; IL-8, interleukin-8; MCP-1, monocyte chemoattractant ...
DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...
The study comprehensively analyzed "cis-regulatory elements" (CREs), which are the DNA sequences ... including enhancers and promoters, are essential for controlling when and where genes are ...
RNA polymerase binds to a region just before the gene, called the promoter, before moving down the DNA to the gene. Enhancers are regions of DNA that act as molecular switches for turning genes on or ...
This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...
The numbers of the principal regulatory elements present in insulin promoters are listed. Given the complexity and uncertainty of predicting the transcriptional outcome of mutations within ...