Cis-regulatory elements (CREs)—including promoters, enhancers, silencers, and insulators—are critical non-coding DNA ...

Promoter recognition in various organisms is an area of interest in bioinformatics. In this paper, a feed-forward neural network classifier is presented to predict promoters in three organisms using a ...

Gene relation prediction is crucial for understanding cancer pathways and developing targeted treatments. This study proposes a novel Graph Transformer Network to predict gene relations by integrating ...

DeepMind has launched AlphaGenome, a new artificial intelligence (AI) model that can predict how single DNA variants affect gene regulation across the human genome. The model, now available via API ...

The numbers of the principal regulatory elements present in insulin promoters are listed. Given the complexity and uncertainty of predicting the transcriptional outcome of mutations within ...

The DNA molecule shows the unique advantages in the “gene-like” construction of functional materials, mainly including the precise arrangement of bases (monomers), the controllable design and assembly ...

Unlocking the Potential of Minicircle DNA A fully synthetic, cell-free approach to mcDNA production could unlock new possibilities for safer, more efficient gene therapy.