Recent years have seen an upsurge of brain imaging, with renewed interest in techniques like electron microscopy, which allows us to observe and study the architecture of the brain in ...

Imagine owning a camera so powerful it can take freeze-frame photographs of a moving electron—an object traveling so fast it could circle the Earth many times in a matter of a second ...

History and principles Freeze-fracture electron microscopy has been firmly established as a major technique in ultrastructure research for well over 30 years. Although elements of the technique in ...

A team of researchers has developed the first transmission electron microscope which operates at the temporal resolution of a single attosecond, allowing for the first still-image of an electron ...

An alternative method, called cryo-electron tomography (cryo-ET), provides clearer images of the brain's smallest parts in a more native state, however, it requires freezing.

To be able to see axons on brain cells (neurons), which are 100 times smaller than the width of a human hair, the scientists used high pressure freezing electron microscopy.

Transmission electron microscopy reveals the architecture of cells at nanometer resolution, but chemical fixation severely warps their native structure. The true ultrastructure of cells can be ...

Using technologies like electron microscopy (EM) it is possible to capture molecular mechanisms in great detail, but not when these mechanisms are currently moving. The field of cryomicroscopy ...

FREEZE-FIXATION implies rapid freezing of small specimens followed by vapour fixation at a low temperature. This method differs from freeze-drying by not removing the water of the specimen before ...

The researchers claim LICONN is the first technology beyond electron microscopy (EM) that is capable of reconstructing brain tissue with all the synaptic connections between neurons.

After the brain was cryofixed and embedded, it was observed and photographed in using 3D electron microscopy. The researchers then compared the cryofixed brain images to those taken from a brain ...

World’s Fastest Microscope Can See Electrons In Freeze-Frame Motion The newly developed device captures moments a quintillionth of a second long.