Imagine a cancer treatment that precisely targets malignant cells, leaving healthy ones untouched. Consider, also, a cancer treatment that corrects abnormal protein synthesis to produce healthy ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...

In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks ...

Johns Hopkins University School of Medicine researchers have discovered a dual regulatory mechanism safeguarding ...

This study is the first to demonstrate that certain tRNA introns influence gene expression. Scientists have discovered that ...

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts.

Both Tabrizi and Yang think that knocking down MSH3 could stave off HD pathology. Tabrizi noted that MSH3 also modifies other run-on repeats, including those causing fragile X syndrome, myotonic ...