First, whole microorganisms can transiently exist in the extracellular space and be taken up by DCs into the endocytic pathway, where relevant antigens are loaded onto MHC class II molecules in ...

“Moreover, the enrichment analysis revealed that it is involved in biological functions and pathways such as endocytic vesicle, scavenger receptor activity, and phagosome,” the authors note ...

The molecular players and pathways involved in internalization and recycling have previously been studied in model cell lines such as HeLa. However, dendritic cells (DCs), which rely on a specialized ...

We also observed that 40 plasma proteins increased and 4 plasma proteins decreased in the OIR subjects compared to the LIS subjects, and most proteins are involved in metabolic and endocytic functions ...

Despite the established links between inflammation and cancer development, the effects of inflammatory signaling on cancer ...

The way you personalize that experience is through this lever of career pathways. Each student has their own lever of engagement in school, but fully developing pathways helps meet the needs of a ...

The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...

Digital technologies and AI are disrupting the way people live, work, and learn. At the same time, education systems need to become both a rapid producer and an avid consumer of digital and data ...

MANILA, Philippines — A bill to allow graduating junior high school students to pick alternative education pathways has been approved on third and final reading by the House of Representatives ...

Overall, digital pathways in education and skills development can be seen as the interplay of two dimensions: (1) depth of digital transitions, the extent to which public policy efforts take a ...

Endosomal recycling is a branch of intracellular membrane trafficking that retrieves endocytosed cargo proteins from early and late endosomes to prevent their degradatio ...