A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

Researchers at the University of Gothenburg, Sweden, have uncovered a critical mechanism that may pave the way for innovative ...

New research in eGastroenterology identifies the unfolded protein response (UPR) as a crucial mechanism in maintaining ...

They found that the inner lining of the upper intestine, called the "epithelium" –composed of a variety of cells that are not classically part of the immune system – also plays an active role ...

In vivo, the intestinal epithelium interacts with the neighboring environment through complex crosstalk, which involves components such as the immune system, tissue microenvironment, and gut microbes.

By reinforcing the gut’s protective barrier, we might prevent bacteria from invading the epithelial cells that line the ...

The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and communication between the gut microbiota and the nervous system.

However, this approach presents distinct challenges: most of these drugs lack target-specificity, leading to off-target side ...

Barrett's esophagus is an acquired metaplastic abnormality in which the normal stratified squamous epithelium lining of the esophagus is replaced by an intestinal-like columnar epithelium.

"By reinforcing the gut's protective barrier, we might prevent bacteria from invading the epithelial cells that line the ...