This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...

Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...

Researchers discovered that gut microbiota-derived hexa-acylated LPS enhances the effectiveness of anti-PD-1 cancer ...

When prescribed to treat cutaneous T-cell lymphoma, methotrexate is used to slow down or stop tumors and plaques from growing on the skin. Brand names: Jylamvo, Rheumatrex, Trexall, Xatmep Interferon: ...

In some experiments, mice were administered recombinant IFN or adoptively transferred with plasmacytoid dendritic cells (pDC). Results Allergic Tlr7 ... between groups was analysed using Student's t ...

Featured here, the Cash Flow Statement for Gamma Communications PLC, showing the changes in the company's cash and cash equivalents, broken down to operating, investing and financing activities ...

In general, chemotherapy medications work by attacking cells or by preventing them from ... When this occurs, your blood isn’t able to clot properly, which can lead to excessive bleeding.

ADI-001 is an allogeneic gamma delta CAR T-cell therapy that targets the B-cell antigen CD20. The Food and Drug Administration (FDA) has granted Fast Track designation to ADI-001 for the treatment ...

Gene signatures identified a prominent response to interferon gamma ... cell sorting and cryopreservation of fresh neutrophils. EK analysed the data. JB and JS performed RNAseq and mass cytometry data ...

The idea of throughput, also known as the flow rate, is part of the theory of ... If the parts don't arrive when ABC Cycles needs them, the company's throughput will be lower.

In this study, for the first time, we show that IFN-α assessed by digital ELISA and IFN-I gene score perform equally for identifying the association of IFN-I with SLE disease activity and clinical ...

1Department of Obstetrics and Gynecology, Peking University Third Hospital, China 2Institute of Medical Innovation and Research, Peking University Third Hospital, Beijing, China. 3Biobank, Peking ...