More information: Shin-ichiro Yoshimura et al, Oxr1 and Ncoa7 regulate V-ATPase to achieve optimal pH for glycosylation within the Golgi apparatus and trans-Golgi network, Proceedings of the ...

The Golgi apparatus serves multiple crucial roles in the cell. These roles include the addition and subsequent modification of glycans, not only to newly-made proteins arriving from the endoplasmic ...

When attached to target proteins, this sequence enhances their interactions with glycosylation enzymes in the Golgi apparatus, leading to significantly increased galactosylation and sialylation ...

The Golgi apparatus is a central organelle of the mammalian secretory pathway. As it is oft-repeated, the Golgi apparatus (and secretory pathway) is responsible for producing, processing and ...

Author Response The following is the authors’ response to the original reviews. Public Review: Lujan et al make a significant contribution to the field by elucidating the essential role of TGN46 in ...

The Golgi body (or Golgi complex, apparatus), and Endoplasmic reticulum (ER) are both organelles found in the majority of eukaryotic cells. They are very closely associated and show both ...

While plant cells have obvious differences to those of animals, all of us with complex – eukaryotic – cells have a Golgi apparatus ‘post office’ within each one.

Glycoproteins are formed through glycosylation, which is a complex and reversible enzymatic reaction that transpires across all domains of life. 2 Glycosylation can occur as a type of ...

The study, published in the journal Stem Cell Reports, found that during glycosylation, the MGAT5 enzyme significantly regulates the formation of neurons and astrocytes from neural stem cells.

N-linked glycans, such as Asn 234, on wild-type SARS-CoV-2 S glycoprotein trimer are modified in the Golgi-complex of the host cell.