Trimethylation of histone H3 at lysine 4 (H3K4me3), is a type of histone modification that usually occurs during active gene transcription when the cell reads the gene to make a protein.

A greater challenge on PTM complexity lies on the landscape of histone H3, which has been reported to be decorated with a much larger number and variety of modifications than any of the other ...

Creative Proteomics, a global leader in proteomics and bioanalytical services, has launched its state-of-the-art N-terminal Edman Degradation service, offering researchers a precise and reliable ...

Histone modification is an epigenetic mechanism that enables fine-tuning of gene expression. Mutation or dysregulation of proteins associated with histone modification (called “writers,” “erasers,” ...

Creative Diagnostics now provides scientists with various tools for accurate quantification and identification of tRNA modifications within complex biological samples, such as the Anti-2'-O ...

Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication.

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

Mass spectrometry-based proteomics has begun to play a significant role in the interrogation of histone PTMs, revealing many new aspects of these modifications that cannot be easily determined ...

Creative Proteomics, a renowned leader in the field of proteomics services, is proud to announce the launch of its cutting-edge Exosome Proteomics service. Leveraging years of expertise and ...

The Histone PTMs Analysis Service by Creative Proteomics aims to cater to this specific scientific need. Using cutting-edge technologies, such as mass spectrometry, liquid chromatography, and ...