Genome-wide association studies (GWAS) often turn up a long list of genes that MIGHT help cause the trait of interest. ... Reporting May 2nd in the American Journal of Human Genetics, ...

In human and yeast research, GWAS limitations might be overcome, at least partially, by ever increasing the sample sizes. This is not straightforward with flies, ...

When one of these SNPs occurs more frequently with a given condition, “it is considered to mark a region of the human genome that influences the risk of disease.” Disease is perhaps too strong a word; ...

Your DNA has long been known to play a role in shaping your personality. Now, researchers at Yale School of Medicine (YSM) ...

Largest ever multi-ancestry GWAS meta-analysis of bipolar disorder provides novel insights into the genetic basis of bipolar.

Novel approaches integrating GWAS studies with transcriptome (TWAS) or proteome (PWAS) data is a promising way forward to pinpoint affected genes (Gusev et al., 2016; Suhre et al., 2021). Wingo et al.

Of 14 metabolites identified, 2 appeared to have “robust” causal relationships with idiopathic pulmonary fibrosis.

“Short-lived organisms represent a fundamentally different evolutionary strategy, and the idiosyncrasies influencing their aging may not apply to longer-lived models, including humans,” researchers ...

Dogs are a compelling model of human obesity, in part because they develop obesity due to similar environmental influences as ...

A large-scale genome-wide association study (GWAS) using data from the United States Department of Veterans Affairs (VA) Million Veterans Program (MVP) – one of the largest US-based biobanks ...

Background: Few genome-wide investigations have examined germline variants associated with mCRC outcomes following primary treatment. Here, we performed a GWAS meta-analysis to explore the impact of ...