In vivo, αKG supplementation and OGDH suppression both increased the number of goblet and Paneth cells and raised intestinal 5-hydroxymethylcytosine (5hmC) levels.

Appendix cancer is a rare but increasingly recognized malignancy, often discovered incidentally during surgery for presumed ...

RESULTS Cells in focal patches of gastric metaplasia contained secretory granules of both gastric and goblet cell phenotypes. MUC5AC and TFF1 were present as expected in gastric foveolar cells but in ...

The totality of bacteria, viruses and fungi that exist in and on a multicellular organism forms its natural microbiome. The ...

Intestinal stem cells are multipotent adult stem cells, which in mammals reside in the base of the crypts of the adult intestine. Intestinal stem cells continuously self-renew by dividing and ...

Research carried out on mice has revealed how a hormone released by the intestine acts on the brain and helps regulate the ...

Up to half of patients with Crohn's disease, an inflammatory bowel disease, develop a complication called fibrosis, where the ...

During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo. The cells ...

Goblet cell carcinoid (GCC): A rare appendiceal tumour showing features of both neuroendocrine and adenocarcinoma cells. Appendiceal neoplasm: Any abnormal growth arising from the appendix ...

Objective: In mice, a subpopulation of gut dendritic cells (DCs) expressing CD103 drives the development of regulatory T (Treg) cells. Further, it was recently described that the cross-talk between ...

Therapeutic effects of natural products against relative diseases by targeting intestinal mucosal immunity; 5. The target immune cells or signaling pathways involved in the modulation of natural ...