Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

For example, a person who weighs 60 kg (132 lb) should consume 1,200 mg (1.2 g) of isoleucine per day. Meeting these requirements is very easy with most diets, so there’s usually no need to ...

MANILA, Philippines — A submarine drone suspected to be from China was recovered in waters off the central Philippines, police said on Thursday, warning of “potential national security implications.” ...

aCenter for Renal Translational Medicine/Institute for Metabolomic Medicine, University of California San Diego, San Diego, CA, United States bDepartment of Clinical and Molecular Medicine, Faculty of ...

An Intertropical Convergence Zone (ITCZ), shear line and the Northeast Monsoon (Amihan) will affect the country on Wednesday, bringing rains on New Year's Day, PAGASA reported. The ITCZ will be ...

MANILA, Philippines — Fans of luxury hotel chain Four Seasons — who must be wondering why the hospitality brand has so far skipped the Philippine market — now need not fret. We hear that ...

Cascade reaction systems (200 μL reaction volumes) were prepared in which the following conditions were varied: pH (5.5–10), sucrose concentration (100–1,000 mM), concentration of UGT94D1-F119I/D188P ...

Capital structure is the mix of debt and equity that fund a company's operations. A judicious use of debt and equity is a key indicator of a strong balance sheet. A healthy capital structure that ...

Table 1 Crystallographic data and refinement statistics for alanine:glyoxylate aminotransferase 1 (AGT1) crystals. In the AGT1 structure crystallized in the ... 100 mM Tris-HCl pH 8.5) and precipitant ...