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Gene expression is an essential process that happens inside cells to translate genetic information into usable products such as proteins that are important for the development, structure ...

Using this system, we demonstrate programmable insertion of a 1.1 kb gene expression cassette into specific genomic loci of human cell lines and primary T cells. Mechanistic studies reveal that CREATE ...

retinal cells or neurons ― measuring, among other things, gene expression and the binding of key proteins called transcription factors. “This is a field poised to have this type of advancement ...

the model can predict gene expression in unseen cell types with high accuracy. It has already uncovered mechanisms driving a pediatric leukemia and may help explore the genome’s “dark matter,” where ...

In the new study, Rabadan and his colleagues tried to use AI to predict which genes are active within specific cells. Such information about gene expression can tell researchers the identity of ...

Concurrently, numerous genes related to vitamin response, brown adipocyte differentiation, T cell differentiation, hormone secretion, hemostasis, peptide hormone response, steroid metabolism, and ...

This selective gene inactivation, known as monoallelic expression, affects about 1 in 20 genes and varies between cell types. The study shows that in families with genetic disorders, the active copy ...

Proteo-Science Center, Ehime University, 2-5 Bunkyo, Matsuyama, Ehime 790-8577, Japan ...