This manuscript describes an important finding of the transcriptional control of a chimeric gene transfer agents (GTA) cluster in Bartonella by a processive anti-termination factor (BrrG). The ...

Phage biology is the scientific discipline concerned with the study of all biological aspects of bacteriophages (phages), which are viruses that infect bacteria. This includes the distribution ...

Whilst the ultimate outcome of the lytic cycle is production of new phage progeny and death of the host bacterial cell, this is a multistep process involving precise coordination of gene transcription ...

The therapeutic use of phages to treat bacterial infections (“phage therapy”) was conceived by Felix d’Herelle nearly a century ago. However, its power has been realized only recently, largely due to ...

Zhejiang Tiantong Forest Ecosystem National Observation and Research Station, Center for Global Change and Ecological Forecasting, School of Ecological and Environmental Sciences, East China Normal ...

One of these has been to rescue phage therapy from history, which consists of using bacteriophage viruses (phages) to exterminate resistant bacteria. Thousands of treated patients have demonstrated ...

aeruginosa infections in animal models and are associated with worse skin and lung infections in humans. Here we review the biology of Pf phage and what is known about its contributions to ...

Shelby is an assistant editor for The Scientist. She earned her PhD from West Virginia University in immunology and microbiology and completed an AAAS Mass Media fellowship.

5. Interindividual and methodological variations hinder the generalisability of IBD-related virome biomarkers. 6. Phage therapies, though currently restricted to compassionate use, have demonstrated ...

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