Our cells' identity is shaped by DNA tags called methylation. New tech, scDEEP-mC, maps these tags in single cells with ...

Microglia are specialized immune cells that make up around 10 % of all cells in the brain and spinal cord. They work by removing pathogenic bacteria, dead cells, aggregated proteins, and soluble ...

A stem cell platform aims to recreate the brain's immune system using lab-grown human microglia cells, to understand how it functions – and fails – in neurodegenerative disease.

Microglia are a specialized type of immune cell that accounts for about 10% of all cells within the brain and spinal cord. They function by eliminating infectious microbes, dead cells, and aggregated ...

Abstract We have generated a single-cell RNA sequencing atlas of peripheral blood and ventricular CSF in idiopathic normal pressure hydrocephalus (iNPH) patients totaling 140,207 single-cell ...

Scientists achieved “a milestone” by charting the activity and structure of 200,000 cells in a mouse brain and their 523 million connections.

Using a single-cell sequencing technique, Brazilian researchers have created the first cell atlas of focal cortical dysplasia (FCD), a malformation of the cerebral cortex that leads to drug ...

This study aims to elucidate IS-induced transcriptomic changes in ASTs, OLs, and OPCs using single-cell RNA sequencing (scRNA-seq) of human brain tissues. We hypothesize that IS triggers distinct ...

Strokes lead to irreversible damage to the brain and are one of the most common causes of dependency or death.

In this study, we explored sex-specific patterns of gene expression in different brain regions that have been associated with psychiatric disorders in rats using RNA-seq and snRNA-seq. We used ...