Johns Hopkins University School of Medicine researchers have discovered a dual regulatory mechanism safeguarding ...

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts.

Rett syndrome is a rare genetic disease affecting 1 in 10,000 newborn girls, characterized by sudden regression around 1 year ...

This parent-child relationship helps regulate brain regeneration and repair ... system made it possible to assess the functional activity of neural stem cells. Single cell sequencing and spatial ...

R package with collection of functions created and/or curated to aid in the visualization and analysis of single-cell data using R.

29Developmental Biology and Cancer Department, UCL GOS Institute of Child Health, London, United Kingdom. 32Haematology and Oncology Department, Great Ormond Street Hospital, London, United Kingdom.

memento is a Python package for estimating the mean, variability, and gene correlation from scRNA-seq data as well as contructing a framework for hypothesis testing of differences in these parameters ...

This study aims to elucidate IS-induced transcriptomic changes in ASTs, OLs, and OPCs using single-cell RNA sequencing (scRNA-seq) of human brain tissues. We hypothesize that IS triggers distinct ...

Neurons are cells in the body that are responsible for transmitting electrical signals through the nervous system. Different types of neurons affect the ability to move, which begins as an impulse, or ...

The research represents an important step toward untangling the complex interplay of immune cells in the brain. If replicated in further animal studies and confirmed in humans, the research could ...

Harvard Medical School research reveals highly specialized regulatory T cells that curb inflammation and act as gatekeepers to protect the inner regions of the brain. The work, which was done in mice, ...