A multi-omics study reveals that impaired branched-chain amino acid (BCAA) catabolism is a key driver of sarcopenia, ...

Although the metabolic functionalities of astrocytes are well known, their relationship to neurological disorders is poorly understood. The ways in which astrocytes regulate the metabolism of glucose, ...

In proximal tubules, glutamine uptake requires complete metabolism of glutamine through the involvement of root tip Na+ dependent neutral amino acid transporter ... to participate in the tricarboxylic ...

In localized non-small cell lung cancer (NSCLC), a tumor's ability to use carbon from glucose to feed the tricarboxylic acid ...

Given that the role of PRMT1 in metabolic regulation has been well-documented, we then investigated whether PRMT1 is involved in transforming 6133 cells through metabolic reprogramming. To assess this ...

These include amino acids, which are the molecules that make up proteins, as well as nucleobases - the fundamental components of DNA. This doesn't mean there was ever life on Bennu, but it ...

Of the 20 essential amino acids, nine are actually essential. Of those nine, three are branch-chain amino acids (BCAAs). Leucine falls into both groups. All BCAAS are vital for building and ...

This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance ... All blood samples were collected before the first trastuzumab treatment cycle. Samples ...

Then, at university, lecturers told us to use more scientifically accurate names for the major metabolic pathways. ‘Krebs’ became the tricarboxylic acid (TCA) cycle, and ‘Calvin’ became the reductive ...