Loss of synapses and dysfunctional synapses in a region-specific way is important in Alzheimer’s. It’s actually the strongest correlate of cognitive decline, far more so than plaques and tangles, ...

Replacing mutated microglia with healthy microglia halts the progression of the genetic neurological disease adult-onset ...

Alzheimer's disease progression linked to microglia fat metabolism, potential new treatment target identified in recent study ...

New research has identified the gene Egr-1 as a critical regulator of immune balance, offering hope for autoimmune disease therapies.

A team at Scripps Research has created a microchip that can rapidly reveal how a person's antibodies respond to viruses using only a drop of blood. This game-changing technology, called mEM, condenses ...

Glial cells support neurological structures, function, cognition, behaviours, physical skills, and motor coordination.

An international research team has deciphered a mechanism of the evolutionary arms race in human cells. The findings provide ...

Replacing defective microglia can halt ALSP—a fatal neurodegenerative disease—in mice and humans, offering hope for broader brain therapies.

The researchers discovered that STING, an immune molecule meant to protect the brain, may actually be making things worse as ...

Microglia replacement therapy helps treat people with a rare genetic condition called ALSP, suggesting the approach could ...

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive neurological disease with an ...