Mechanistic discrepancies between species highlights the limitations of mouse models in advancing STING inhibition drugs for various diseases.

Researchers have long focused on the STING (Stimulator of Interferon Genes) pathway as a way to harness the immune system's natural defenses against ...

Ansari-Lari, M.A. et al.Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6.

A mouse watched YouTube. Then scientists mapped a tiny piece of its brain. Scientists say the map of a speck of a mouse's brain could be as transformative as the Human Genome Project.

Today, researchers have generated over 5,000 mouse models with genotypes for about 1,500 human diseases. This includes genetically inherited conditions, neuromuscular disorders, mental conditions ...

They gave it something much smaller — a tiny stretch of human DNA known as HARE5. And in return, the mouse grew a brain about 6.5% bigger than its peers. The tweak was minuscule.

Scientists achieved “a milestone” by charting the activity and structure of 200,000 cells in a mouse brain and their 523 million connections.

Enor-mouse news At 9 years & 209 days old, Pat the Pacific pocket mouse is officially the oldest living mouse in human care & was honored with the @GWR title today. This news is a big win for the ...

Putting the uniquely human version of a certain gene into mice changed the way that those animals vocalized to each other, suggesting that this gene may play a role in speech and language.

The experiments mark the first time fully synthetic mouse embryos — without the use of sperm or eggs — have been grown outside the womb.