Rational drug design depends on the knowledge of the three-dimensional (3D) structure of complexes between proteins and lead compounds of low molecular weight. A novel nuclear magnetic resonance (NMR) ...

Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

Dr Jon Major, a Reader in the Department of Physics and the Stephenson Institute for Renewable Energy, is the winner of the ...

Analytical chemistry researchers at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences (HIMS) have ...

Vibration isolation is crucial for NMR spectroscopy accuracy. TMC's STACIS 4® and MaxDamp® systems significantly reduce floor ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

NMR Structure of the Second Intracellular Loop of the α2A Adrenergic Receptor: Evidence for a Novel Cytoplasmic Helix †, ‡ Duane A. Chung , Erik R. P. Zuiderweg , Carol B. Fowler , Orkun S. Soyer , ...

Structure verification by NMR is a vital task in drug discovery but can be slow and subjective. This article explores how ASV ...