Antidepressants, especially selective serotonin reuptake inhibitors (SSRIs) like fluoxetine (Prozac) or sertraline (Zoloft), ...

Speedballing – the practice of combining a stimulant such as cocaine or methamphetamine with an opioid such as heroin or ...

Speedballing—the practice of combining a stimulant like cocaine or methamphetamine with an opioid such as heroin or ...

MIRA is advancing complementary non-opioid therapies for two of the largest pain markets MIAMI, FLORIDA / ACCESS Newswire / ...

Northwestern Medicine investigators have identified a surprising culprit in the progression of inflammatory bowel disease: a ...

By Priscilla Tenorio Getty Images To know how opioids affect communities all around us, we must first know what opioids are and how we are affected by them even in ways we do not realize. According ...

Five times stronger than morphine, [9] hydromorphone also has renally cleared metabolites; however, owing to its higher potency, a much smaller dose can be used for an equianalgesic effect.

The direct side effects and side effects from metabolites of most opioids are similar ( Table 2 ). [17] Direct side effects usually appear early on in therapy and often improve over time.

When one takes an opioid, the chemical compounds found in the drug act as an agonist to neurotransmitters in the brain, mimicking the pleasurable feelings of a dopamine rush. Opioids also inhibit ...

Local governments and the State of Iowa are expected to receive $37.8 million from a multi-billion dollar settlement with Purdue Pharma, the makers of OxyContin, and its owners, the Sackler family, ...

Purdue Pharma’s $7B opioid settlement could advance soon after states back it by: GEOFF MULVIHILL, Associated Press Posted: Jun 18, 2025 / 01:45 PM CDT Updated: Jun 18, 2025 / 01:47 PM CDT ...