Ectopic expression, gene knockdown and CRISPR/Cas9-mediated knockout studies of mutant p53 were performed to investigate p53-dependent drug effects. p53 signalling was examined using quantitative ...
RPE1 p53 KO, HCT116 p53 KO, RPE1 (H2B-RFP), MDA-MB-231 (H2B-mCherry), and Cal51 (Tubulin-mNeonGreen and H2B-mScarlet were endogenously tagged by CRISPR-Cas9) cells were originally obtained from Dr.
P53 and PI3K/Akt are important pathways by which MEG3 participates ... leading to cell apoptosis. MEG3 gene knockout significantly increased the viability of HTR-8/SVneo cells and reduced cell ...
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Bare-knuckle boxer Kaine Tomlinson Jr terrified fans inside with his brutal knockout at BKFC's KnuckleMania V. The KO of opponent Pat Sullivan inside Philadelphia’s Wells Fargo Center was so ...
Jeremy Stephens def. Eddie Alvarez via third-round TKO (5:00) Ben Rothwell def. Mick Terrill via first-round KO (0:36) All former UFC heavyweight Ben Rothwell needed was 36 seconds to become the ...
In Tokyo, Japan, Naoya Inoue, the undisputed super bantamweight champion, successfully retained his titles on Friday morning with a fourth-round KO win over Ye Joon Kim. Inoue increased his ...
Born as a pandemic diversion in 2020, “Knockout” is finally a fully baked dance performance, premiering with a two-week run kicking off the spring edition of Steppenwolf’s LookOut Series.
The UEFA Champions League's first-ever league phase came to a dramatic close on Wednesday, setting up for an equally entertaining knockout stage that begins in two weeks' time. The introduction of ...