Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.
Dr. Suneel Kamath discusses the ALASCCA study in colorectal cancer and highlighted the importance of next-generation ...
However, mechanistic studies to support the conclusion that mitochondrial function is increased in the tumours remain incomplete and would benefit from experiments that would directly interrogate ...
Both television and cinematic content of the ever-evolving Western genre have found their place in the digital library of Netflix, which houses some of the most compelling TV shows in the genre. This ...
College of Life Sciences, Key Laboratory of Animal Reproduction and Biotechnology in Universities of Shandong, Qingdao Agricultural University, Qingdao 266109, China ...
The DF-O and MPs samples suppressed autophagy by decreasing expression levels of microtubule-associated protein light chain 3 (LC3B), p-phosphatidylinositol 3-kinase (p-PI3K), phosphorylated AKT ...
On a recent winter afternoon in downtown Truckee, the sun dipped behind the mountains as a full moon rose above Donner Pass Road, the California city’s main thoroughfare. As the temperature ...
More recently, quantitative proteomics analyses uncovered the heterogeneity of Western AML patients at ... molecular characteristics of Acalisib (PI3K inhibitor) resistance. In the Spearman ...
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