Inhibition of LKKR2 may rescue neurons that are dying due to a type of Parkinson’s disease that is caused by a single genetic ...

Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a ...

The results of experiments in mice models were "astounding," said biochemist Suzanne Pfeffer of Stanford University.

Scientists at the University of Western Australia and the Perron Institute for Neurological and Translational Science have ...

The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...

Signaling Pathways Regulating Osteoblast Differentiation & Bone Formation . Osteoblast differentiation is predominantly regulated by Wnts, which are mammalian homologs of the Drosophila secreted ...

Additionally, PE interfered with and attenuated the interaction between P2X7R and PIP2, displaying strong docking activity with P2X7R.Taken together, PE exhibited significant anti-myocarditis activity ...

Depletion of signaling lipid phosphatidylinositol,4-5-bisphosphate (PIP2) from the inner leaflet of plasma membrane (PM) is linked to heart failure, Alzheimer’s, cancer, and other diseases. We show ...

Various signaling pathways guide the organization of cells and tissues in the body. Among these is the Bone Morphogenetic Protein (BMP) pathway, which plays a vital role in instructing early ...

Patients with stage I-III rectal cancer or stage II-III colon cancer exhibiting somatic alterations in the PI3K signaling pathway were included. Patients were randomized to receive either 160 mg of ...

Kahn et al. demonstrate how TGFb signaling adds to the complex constellation of signaling pathways that regulates myofibroblasts during the formation of the alveolar wall. While TGFb signaling was ...