earth28d
First total synthesis of mushroom compound could transform medicine
A recent breakthrough by researchers from Shinshu University, Japan, is changing this landscape. The team has successfully achieved the first total synthesis of inaoside A, a natural compound found in ...
Phys.org1mon
Researchers report the first-ever total synthesis of a promising mushroom-derived compound
"Although the α-D-ribofuranoside structure is frequently found in natural products, there have been fewer reports of the synthesis of α-D-ribofuranosides than of the β-anomers. Thus, the ...
C&EN1mon
Design and Synthesis of Hederagenin Derivatives for the Treatment of Sepsis by Targeting TAK1 and Regulating the TAK1-NF-κB/MAPK Signaling
School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and ...
GitHub9mon
audio-synthesis
Amphion (/æmˈfaɪən/) is a toolkit for Audio, Music, and Speech Generation. Its purpose is to support reproducible research and help junior researchers and engineers get started in the field of audio, ...
Frontiers3y
Sex Differences in Pulmonary Hypertension
Overview of sex hormones synthesis, metabolism and main effects in humans and ... ERAs), nitric oxide (phosphodiesterase-5 inhibitors and guanylate cyclase stimulators) and prostacyclin (prostacyclin ...
Frontiers11y
Proinflammatory and immunoregulatory roles of eicosanoids in T cells
The rate-limiting and tightly regulated lipoxygenases control synthesis of LTs while the equally well-controlled cyclooxygenases 1 and 2 generate prostanoids, including PGs, PCs, and TXAs. While many ...