The findings of two recent studies give hope that the disease could one day be reversed in humans—but experts warn that this ...

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive neurological disease with an ...

Microglia replacement therapy helps treat people with a rare genetic condition called ALSP, suggesting the approach could ...

Scientists at the University of Sydney have uncovered a malfunctioning version of the SOD1 protein that clumps inside brain cells and fuels Parkinson’s disease. In mouse models, restoring the ...

Replacing defective microglia can halt ALSP—a fatal neurodegenerative disease—in mice and humans, offering hope for broader brain therapies.

A groundbreaking study led by Prof. Bo Peng at Fudan University demonstrates that microglia replacement effectively halts the ...

After nearly 15 years' research, scientists at the UdeM-affiliated CHU Sainte-Justine have developed a compound that has ...