Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But ...

Imagine that you want to know the plot of a movie, but you only have access to either the visuals or the sound. With visuals ...

The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component ...

Researchers introduce RhoFold+, a groundbreaking deep learning model that predicts RNA 3D structures with unprecedented accuracy and efficiency, addressing critical challenges in structural biology.

Here we construct a base pair motif library that enumerates the complete space of locally adjacent three-neighbor base pair and records the thermodynamic energy of corresponding base pair motifs ...

A method has been developed for predicting the tertiary structures of RNA–RNA complex structures using secondary structure information and a fragment assembly algorithm. The linker base pair and ...

(D) Tertiary constraints and DAGGER analysis of BASH MaP treated Spinach accurately model Spinach secondary structure. To determine whether tertiary folding constraints could improve Spinach structure ...

Although it is a single-stranded polymer composed of only four nucleotides, RNA possesses an intrinsic ability to fold into complex secondary and tertiary structures, further modulated by ...

A tandem technique for resolving RNA structures Published online 26 July 2022 Combining computational and experimental methods generates atomic-level insights into 3D RNA structures. Michael ...