Each cell of the human body contains two meters of DNA. The whole secret lies in the intricate three-dimensional arrangement that allows DNA strands to be efficiently organized and compacted within ...

This study is the first to demonstrate that certain tRNA introns influence gene expression. Scientists have discovered that ...

BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.

This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...

Share and Cite: Hinz, B. and Kenyon, J. (2025) Getting to a Diagnosis: A Rare Case of TFE3 Translocation Renal Cell Carcinoma ...

There was a very intimate connection." To better characterize the cellular components of brain cancer, investigators performed single-cell RNA sequencing on tissue samples from 33 types of brain ...

Objective Innate immunity plays important roles in pancreatic ductal adenocarcinoma (PDAC), as non-T-cell-enriched tumour. Neutrophils are major players in innate immune system. Here, we aimed to ...

Design We performed single-cell RNA sequencing and spatial transcriptomic analysis in primary colorectal cancer (CRC) and metastases in the liver (lCRC) or ovary (oCRC). We also conducted ...

Using genomic sequencing, the team was able to take 'snapshots' of the human cells and their 'shuffled' genomes over the course of a few weeks ... read out using single-cell RNA sequencing.

The purity of the cell lines was tested using a single-nucleus RNA sequencing (snRNA-seq) approach, which indicated no residual pluripotent stem cell contamination. EHM generated from rhesus ...

to the native DNA and RNA, and then we ... s up to 24 or 48 flow cells [PromethION 24 (P24) and PromethION 48 (P48)]. There’s a big gap for people who want to do a few gigabases or thousands ...