RNA bundled in lipid nanoparticles trains T cells in mice to eliminate cancer. Coupled with noninvasive imaging, researchers ...

Researchers engineered a nanobody-conjugated liposome (A5-LNP-DOX) that targets CD155 and delivers doxorubicin directly to ...

An oral drug called MA-5 can improve both heart and muscle problems in Barth syndrome. Testing the drug on cells from Barth ...

The promise of stem cell therapy is powerful. Scientists can draw versatile cells from the human body and deliver them to repair injuries and fight disease from the inside out.

The promise of stem cell therapy is powerful. Scientists can draw versatile cells from the human body and deliver them to repair injuries and fight disease from the inside out. But not all stem ...

Stem-cell therapies that work: 10 Breakthrough Technologies 2025 After years of controversy, stem cells are on the cusp of cures for conditions like epilepsy and type 1 diabetes.

Chimeric antigen receptor (CAR) T–cell immunotherapy re-engineers a patient's immune cells to target cancer cells.

Investigators identified a chemokine/chemokine receptor mismatch for osteosarcoma (i.e., osteosarcomas secrete chemokines for which CAR T cells do not express receptors). The researchers modified ...

They evaluated the homing kinetics (movement) and efficiency of the modified cells – testing their ability to find and infiltrate osteosarcoma.

Findings supported clinical evaluation of CXCR-modified CAR T cells to improve adoptive cell therapy for osteosarcoma patients.

Muse cells for regenerative medicine Given their lack of tumorigenesis, the homing and integration in the damaged tissues, and the non-engraftment in organs and tissues other than the damaged ones, ...

Families pay thousands of dollars to store their children’s stem cells with the hope of a healthier future. But the cells are rarely useful, and sometimes contaminated.