In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

Inositol phosphate metabolites produced by inositol metabolism enzymes serve as vital secondary messengers in eukaryotic ... dimensional structure of the SRF protein. This interaction facilitates the ...

University of Cincinnati Cancer Center researchers looked billions of years into the past to learn more about the potential ...

Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can offer new treatment opportunities.

Carboxy terminal BRCT domains of the breast cancer susceptibility gene 1 (BRCA1) bind to phosphorylated proteins through a pSXXF consensus recognition motif. We report a systematic structure–activity ...